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Validating the authenticity of the pedigrees of Chinese Emperor CAO Cao of 1,800 years ago.
H. Li
Deep pedigrees are of great value for studying the Y chromosome evolution. However, the authenticity of the pedigree information requires careful validation. Here, we validated some deep pedigrees in China with full records of 70-100 generations spanning over 1,800 years by comparing their Y chromosomes. The present clans of these pedigrees claim to be descendants of Emperor CAO Cao (155AD-220AD). Haplogroup O2-M268 is the only one that is enriched significantly in the claimed clans (P=9.323×10-5, OR=12.72), and therefore, is most likely to be that of the Emperor. Moreover, our analysis showed that the Y chromosome haplogroup of the Emperor is different from that of his claimed ancestry of the earlier CAO aristocrats (Haplogroup O3-002611). This study offers a successful showcase of the utility of genetics in studying the ancient history